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DNA-guided CRISPR–Cas12a effectors for programmable RNA recognition and cleavage
Nature Biotechnology · 2026
Thermodynamically programmed one-pot CRISPR platform for point-of-care SNP genotyping
· 2026
Benchtop to at-home test: amplicon-depleted CRISPR-regulated loop-mediated amplification at skin-temperature for viral load monitoring
Biosensors and Bioelectronics, 267 · 2025
DNA-guided CRISPR/Cas effector for programmable RNA-recognition and cleavage
· 2025
DNA hydrogel-interfaced organic electrochemical transistor for the investigation of binding-induced conformational change of small molecule aptamers
ACS Applied Materials & Interfaces, 17(37) · 2025
Structure-enhanced deep learning accelerates aptamer selection for small molecule families like steroids
Briefings in Bioinformatics, 26(6) · 2025 第一作者
Integrating magnetic-bead-based sample extraction and molecular barcoding for the one-step pooled RT-qPCR assay of viral pathogens without retesting
Analytical Chemistry, 95(14) · 2023
Skin-adherent elastomer-hydrogel patch for continuous 12-lead cardiac ambulatory monitoring during physical activities
Advanced Materials Technologies, 8(18) · 2023
Transforming ECG diagnosis: an in-depth review of transformer-based deep-learning models in cardiovascular disease detection
arXiv:2306.01249 · 2023 第一作者
CasMD
蛋白质–核酸分子动力学，化繁为简。
TEMPO
一锅式 CRISPR 分子诊断的配套工具包。
DL-SELEX
结构增强的深度学习，用于适体筛选。
ECG_analysing_app
结合信号处理与深度学习分类的心电图应用。
新会人，潭江边长大。现居香港，香港科技大学生物工程博士在读， 在分子诊断、CRISPR 与适体设计里用 AI 找答案。