Research

1. 2026
   Nature Biotechnology

   DNA-guided CRISPR–Cas12a effectors for programmable RNA recognition and cleavage

   X Wu, WH Lam, Z Zhao, Y Cao, H Lin, X Feng, Y Zhai, IM Hsing

   Read article ↗Earlier preprint ↗Author correction ↗
2. 2026
   Nature Communications, 17, 8376

   Thermodynamically programmed one-pot CRISPR platform for point-of-care SNP genotyping

   X Wu, Y Li, Y Cao, Z Zhao, H Lu, S Liang, GCY Lui, DPC Chan, IM Hsing

   Read article ↗Code ↗Earlier preprint ↗
3. 2025
   Biosensors and Bioelectronics, 267

   Benchtop to at-home test: amplicon-depleted CRISPR-regulated loop-mediated amplification at skin-temperature for viral load monitoring

   Y Cao, H Lin, X Lu, X Wu, Y Zhu, Z Zhao, Y Li, et al.

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4. 2025
   ACS Applied Materials & Interfaces, 17(37)

   DNA hydrogel-interfaced organic electrochemical transistor for the investigation of binding-induced conformational change of small molecule aptamers

   H Lin, Z Zhao, X Feng, SY Yeung, IM Hsing

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5. 2025
   Briefings in Bioinformatics, 26(6)First author

   Structure-enhanced deep learning accelerates aptamer selection for small molecule families like steroids

   Z Zhao, H Lin, HY Lau, H Chen, IM Hsing

   Read article ↗Code ↗
6. 2023
   Analytical Chemistry, 95(14)

   Integrating magnetic-bead-based sample extraction and molecular barcoding for the one-step pooled RT-qPCR assay of viral pathogens without retesting

   X Zhuang, Z Zhao, X Feng, GCY Lui, D Chan, SS Lee, IM Hsing

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7. 2023
   Advanced Materials Technologies, 8(18)

   Skin-adherent elastomer-hydrogel patch for continuous 12-lead cardiac ambulatory monitoring during physical activities

   Y Li, Z Zhao, A Veronica, S Yu Yeung, IM Hsing

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1. 2023
   arXiv:2306.01249Preprint · not peer reviewedFirst author

   Transforming ECG diagnosis: an in-depth review of transformer-based deep-learning models in cardiovascular disease detection

   Z Zhao

   Read preprint ↗

Earlier versions of published work are linked with the journal article above.